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Rose Diamond A Split-thickness graft is used for the shallowest wounds, those that affect only the epidermis and part of the dermis. It is called a split-thickness graft because the doctor removes only a few layers of skin from the donor site. Similar to split-thickness grafts, full-thickness grafts require all three skin layers, the epidermis, dermis and hypodermis, to be removed from the donor site. Full-thickness grafts are often used in cases where the cosmetic appearance of the injured area is very important.
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